Fluconazole In ...
Fluconazole Injection
Fluconazole Injection
Composition
fluconazole and sodium chloridePharmaceutical form
large volume injectionTherapeutic Indications
The product is the widely-used and first-chose medicine for anti-depth portion fungus infection. Mainly treats each kind of fungus infection as moniliasis, cryptococcus sickness, ball spore fungus sickness and so on, including: The mouth swallows and the esophagus rosary fungus infection spreads the rosary sickness. For example: Peritonitis, pneumonia, urine road infection and so on; Rosary fungus vulva vaginitis; the marrow transplants when the patient accepts the cytotoxin class medicine or the radiotherapy, prevents the occurrence of the rosary fungus infection; Treats the new cryptococcus sickness except the meninx.Posology and method of administration
by phleboclysis.the rate of fluid administration should not exceed 5mg/min. Because Fluconazole injection is the diluted chloride sodium solution, the rate of fluid administration should be taken into consideration when used for the patients who is limited in the chloride or solution.1.the treatment of crytococcosis meningitis and other parts infection (such as lung, skin): usually, the first dosage is 400mg, the dosages in the following days are 200-400mg. The course of treatment depends on fungal feedback. But for the cryptococcosis meningitis, the period of treatment of that is 6-8 weeks at least.
2.the treatment of candidiasis blood poisoning and other candidiasis disease:
Usually, 400mg is used in the first day, 200mg the other days. According to the clinical reaction the dosage can be increased to 400mg, one time each day. The course of treatment depends on fungal feedback.
3.for the patients with decreased renal function, the dosage of the first day and second day is as the general dose. After this adjust the dose interval time and dosage according to the ratio.
creatinine elimination ratio interval / daily dosage
40 24 hours (regular dosage)
21-40 48 hours or half of regular dosage
10-20 72 hours or one third of regular dosage
Regular dialysis after each time of dialysis
4.for the children who must be treated with this drug take 3-6mg/kg/day.
Special warnings and precautions for use
(1)pregnant women, suckle women and children are not appropriate to use this product.(2)patients who have tetter after taking the drug should be controlled strictly. If the patients have the speckle, he should be stopped using drug.
(3) For the patients who have to be given Fluconazole more than two weeks or who have accept the treatment of Fluconazole with more than general dose, or other medicines which have potential toxic for the liver and maybe cause hepatic necrosis, they must be examined by heptic function before the treatment. During the course of treatment, heptic function should be re-examined every two weeks.
(4)Interaction: when used with cumoric anhydride, pay attention to adjust the dose of the anti-congelation; used with sulfanilamides and carbamide, pay attention to hypoglycemia reaction.